Plays the ukulele.

After spending years in Chicago theater and building his resume as an actor, at age 28 he relocated to New York City for film and television work.

While in New York, worked as "voice-over talent", including "Secret - strong enough for a man but made for a woman" ("That's my most famous voice-over"). (Esquire, August 1997).

The pop rock band Head Automatica has a song named after the actor called "I Shot William H. Macy"

Appeared, without credit, as a NORAD officer in WarGames (1983).

Was the first choice to voice Marlin in Finding Nemo (2003).

Daughter Georgia Grace born 14 March 2002 in Los Angeles.

Was among the guests at Marcia Cross' wedding to Tom Mahoney

His father lives in Gainesville, Florida.

Studied under David Mamet at Goddard College, Vermont.

His best friends called him "Willie" when he attended Bethany College in Bethany, West Virginia

He attended Allegany High School in Cumberland, Maryland. He was junior and senior class president of his graduating class.

He and wife Felicity Huffman both received Emmy-nominations in 2005

Was a founding member of St. Nicholas Theater in Chicago with David Mamet and writer Steven Schachter.

His agent tried to discourage him from reading the script for Boogie Nights (1997), but he read it anyway, loved it, and signed on to do the film.

In 1985, he and David Mamet co-founded the Atlantic Theater Company, located in New York, New York, USA.

One of his major hobbies is woodworking.

The writers and producers of "The Simpsons" (1989) have joked semi-seriously that if there was ever a live action version of the show, then he would be the perfect choice to play Ned Flanders.

Lived with Felicity Huffman for 15 years before they married in 1997.

Uses the name William H. Macy so he won't be confused with 1970s comedian Bill Macy.

Auditioned for the role of "Brian" on "Family Guy" (1999).

Met Felicity Huffman when she was one of his students at the Atlantic Theater Company

He, wife Felicity Huffman, Giancarlo Esposito and TV stars Camryn Manheim and Kristen Johnston are all members of the New York-based Atlantic Theater Company.

Owns a home in Vermont.

He and his wife Felicity Huffman welcomed their first child, Sofia Grace, on August 1, 2000.

Became a spokesperson for United Cerebral Palsy after filming Door to Door (2002) (TV).

Remembers jokes and always tells one when he appears on "Late Night with Conan O'Brien" (1993).

Owns a Bernese Mountain Dog that was bought in Grass Valley.

Has admitted to experimenting with LSD in college. William stated some friends referred to him as "acid head".