Starred in a season three episode of "Gilmore Girls" (2000), which was the backdoor pilot for a California-set spin-off titled "Windward Circle", that was to have starred Ventimiglia, Sherilyn Fenn and Rob Estes. The network dropped the project citing cost issues due to filming on location in Venice, California.

His Favorite Bands are The Strokes, Deftones, A Tribe called Quest, The Hives.

Close friend of Sophia Bush.

His favorite book is The Long Walk (Richard Bachman).

Similar to his fellow Gilmore Girls cast, also donates to the Pediatric Brain Tumor Foundation, one of his favorite charities.

Close friend of Heroes co-star Kristen Bell.

Started a production company named DiVide Pictures (or the Divide Social Club) with 2 childhood friends.

He was with his co-star Ali Larter on the Red Carpet of Golden Globe 2006.

Milo and `Heroes` co-star Adrian Pasdar auditioned for roles in the proposed Gilmore Girls spinoff where Milo was to be the son of Pasdar`s character. As there are only 12 years difference between them, the casting director said they would be better off playing brothers. Eight years later, they were playing brothers Peter (Milo) and Nathan (Pasdar) Petrelli in `Heroes`.

He has a `67 Chevelle Super Sport named "Evelyn".

He is of Sicilian Italian descent on his father`s side and a combination of Irish, English, Scottish, French, Cherokee and Blackfoot descent on his mother`s.

Made his debut in "The Fresh Prince of Bel-Air: Bourgie Sings the Blues (#6.4)" (1995).

He attended El Modena High School in Orange, CA. He graduated in 1994.

The part of Chris Pierce on "American Dreams" was written specifically for him after he met with the show`s creators.

Didn`t have to audition for "The Bedford Diaries". The WB had Milo, and only Milo, in mind for the role.

Directed the 2003 and 2004 WB Image Campaigns for popular shows such as "Gilmore Girls" (2000), "One Tree Hill" (2003), "7th Heaven" (1996), etc... Some of the WB stars he directed included David Boreanaz, Tom Welling, Kristin Kreuk, Michael Rosenbaum, Jamie Kennedy, James Marsters, Rose McGowan, Allison Mack, Chad Michael Murray, James Lafferty, Beverly Mitchell and `Reba McEntire`.

The "Gilmore Girls" (2000) spin-off (which was to be titled "Windward Circle") has been canceled due to the high cost of filming on location in Venice, California.

He has a great interest in directing.

Originally auditioned for the role of Clark Kent in "Smallville" (2001). Although the role went to Tom Welling, the producers at WB liked him so much they gave him the role of Jess on "Gilmore Girls" (2000).

His smile is his trade mark.

Has been a vegetarian since childhood.

Is best friends with `Heroes` co-star Adrian Pasdar.

He and Bo Barrett once traded seats on an airplane having no idea who each other were.

After the proposed spin-off series for his character "Gilmore Girls" (2000) character Jess fell apart, he chose not to reprise the role as a regular again on the series, citing that he feels that the character has "run his course" [He returned a few times for guest spots].

When he was seven, his two sisters used to dress him up like Madonna!

Has signed on for at least 6 episodes of a currently untitled spin-off of "Gilmore Girls" (2000). The series will focus on the relationship between Jess, his character from "Gilmore Girls" (2000), and his estranged father.

Boyfriend of "Gilmore Girls" (2000) co-star Alexis Bledel from 2002 to 2006.