Twins sons Eric and Derick born in 1985 with Connie Smith, a long time Missouri girlfriend.

His current backing band involves people like guitarist Andy Fairweather-Low (ex-Amen Corner) and bassist Nathan East (Fourplay).

Created his own band, Derek and the Dominoes, after the break-up of Cream.

Mentioned in the song "Life Is a Rock But the Radio Rolled Me" by Reunion.

Was very good friends with Duane Allman, and they held a great deal of respect for each other. Allman played guitar on the Derek and the Dominos song "Layla."

Shortly after the formation of Cream in 1966, the trio got a chance to jam with Jimi Hendrix. Hendrix was a fan of Clapton, and wanted a chance to play with him on stage.

Played guitar on Phil Collins' hit "I Wish It Would Rain Down".

Has owned a string of Ferraris.

He was voted the 53rd Greatest Rock 'n' Roll Artist of all time by Rolling Stone.

While many people believe his nickname "Slow Hand(s)" is because his fingers are slow on the guitar, it is actually because once during a concert he played his guitar so hard that one of its strings broke, and he took time out to re-string it. As he did, the fans in attendance began a "slow hand" clap.

3/10/91: His son Conor, with Lory Del Santo, died in a fall from a 53rd-floor apartment. Clapton's Grammy-winning hit song "Tears in Heaven" was dedicated to the memory of his son.

2/1/05: Daughter Sophie Clapton born.

May 2005: Reunited with Ginger Baker and Jack Bruce for a Cream reunion concert.

Cream: Royal Albert Hall, London May 2-3-5-6 2005 (2005) (V) was the first time Cream had played together since their 1993 induction into the Rock and Roll Hall of Fame.

He owned and played a Gibson Byrdland guitar designed by famous guitarists Hank Garland and Billy Byrd.

1987: Winner of the British Phonographic Industry Award for Outstanding Contribution.

Once while playing a Cream concert, he suddenly stopped playing, and neither Ginger Baker nor Jack Bruce noticed.

Upon returning to England after recording the Derek & The Dominos album "Layla and Other Assorted Love Songs," he was supporting a £1,000-per-week heroin addiction.

July 2001: Voted the South East's best guitarist in Total Guitar Magazine's poll of the greatest 12 British guitarists.

Played two farewell concerts on 26th November: Cream's Farewell Concert (1969) in 1968, and The Last Waltz (1978) in 1976. Ironically, it was partially because of The Band's music that he decided to leave Cream in the first place.

Was the guest of honor at the MMA event "Pride Grand Prix 2000 Tournament", and awarded the winner, Mark "The Hammer" Coleman, with the First Prize Trophy.

2003: He was awarded the C.B.E. (Commander of the British Empire) in the Queen's New Year's Eve Honours List for his services to music.

When Clapton appeared at Live Aid in Philadelphia, one of his backing drummers was Phil Collins. Hours before, Collins had appeared at Live Aid's London concert at Wembley Stadium.

While performing "Further On Up the Road" in The Last Waltz (1978), his guitar strap came undone. To cover for him while he fixed it, Robbie Robertson of The Band improvised a guitar solo.

Before the formation of Cream in 1966, he was all but unknown in the United States, having left The Yardbirds before "For Your Love" hit the American Top Ten.

Has ties to both of the Allman Brothers. With Duane Allman`s help, Clapton recorded the album "Layla and Other Assorted Love Songs" in 1970. In 1991, Clapton wrote the score to the film Rush (1991), which featured Duane`s brother, Gregg Allman.

2001: Inducted into the Songwriters Hall of Fame.

1988: He became the first artist to have a Fender Stratocaster signature model.

Enjoys Mixed Martial Arts.

Before becoming a musician, he designed stained glass windows.

Was cured of his heroin addiction through electro-acupuncture; singer Boy George received the same therapy ten years later.

Has an office in Chelsea.

Cream`s hits were "Wrapping Paper", "I Feel Free", "Strange Brew", "Sunshine Of Your Love", "Anyone For Tennis", "Crossroads", "White Room" & "Badge".

Quit The Yardbirds after the band decided to do the more pop sounding song "For Your Love", which was a departure from the more traditional blues songs they had been doing.

1969: Played with John Lennon and Yoko Ono`s Plastic Ono Band at the Toronto Pop Festival. Other members included Klaus Voormann on bass and Alan White (later of Bill Bruford) on drums.

He was also on the short list of guitarists to replace Brian Jones in The Rolling Stones.

Stephen Stills asked him to join Crosby Stills & Nash so that he could help beef up their sound in concert. He refused due to the fact that he was in the middle of forming Blind Faith with Stevie Winwood.

1/14/03: Daughter Ella May born in London.

Expecting second child with wife Melia at end of 2002.

1995: He received the O.B.E. (Officer of the British Empire).

He is the only artist to be inducted into the Rock and Roll Hall of Fame three times: as a member of The Yardbirds (1992); as a member of Cream (1993); and as a solo performer (2000).

Played guitar along with original `Bond` guitarist Vic Flick on Michael Kamen`s theme for Licence to Kill (1989). The duo were filmed "playing" in various London locations for the expected video. However, the producers decided to opt for a song, sung by Gladys Knight, and the Clapton/Flick instrumental has never been released.

1/1/02: Clapton, 56, tied the knot with Melia McEnery, from Columbus, IG, in a low-key ceremony at a church near his home in Surrey, southern England. Guests were told they were attending the christening of the couple`s six-month-old daughter Julie Rose. But after the baptism of Julie Rose and Clapton`s 16-year-old daughter Ruth, the couple were called forward by vicar Rev. Christopher Elson and exchanged marriage vows.

6/13/01: Daughter Julie Rose was born in Columbus, OH, weighing 7 lb. 1 oz. Her mother is Melia McEnery.

Children: daughter Ruth (b. 1985) and son Connor (b. 1986, d. 1991)

Axes of choice include a Fender Stratocaster and a Gibson Les Paul Standard.

Played the guitar solo on George Harrison`s "While My Guitar Gently Weeps" creating a precedent. No other outside musician had ever had such a privilege.

Was a member of The Yardbirds, John Mayall`s Bluesbreakers, Cream, Blind Faith, Delaney & Bonnie & Friends, Derek and the Dominoes.

According to the August 1998 issue of the British rock magazine "Q", Clapton ranks number 10 on the list of the 100 richest rock stars with an estimated fortune of over £75m.

8/21/86: Son Conor born. Mother is Lory Del Santo. Clapton was still married to Pattie Boyd at the time.

Had a daughter with Yvonne Kelly in 1986 - Made public in 1993.

Spouse: Melia McEnery (1 January 2002 - present) 3 children; Pattie Boyd (27 March 1979 - June 1988) (divorced)

(2007) Release of his book, "Clapton: The Autobiography".