Billy attended Parker School in Chicago. Billy attended Harand Camp of the Theater Arts, located in Elkhart Lake, Wisconsin, along with Jeremy Piven.

His voice was used as a sample on Marilyn Manson's Mechanical Animals tour as the intro for the song, "Rock Is Dead". He can be heard on the live album, "The Last tour on Earth" saying, "Ladies and gentlemen, from the dread capital of the world, Hollwood, California, Omega and the mechanical animals".

Is of Greek descent.

Original family name is Tzanetakos.

Is the voice of Broderick 'Brodi' Ford in the EA Sports Big game SSX Tricky (2001) (VG) (for Playstation2, Nintendo Gamecube, Xbox).

His voice was used as a sample on Marilyn Manson`s Mechanical Animals Tour as the intro for the song Rock Is Dead. He can be heard on the live album The Last Tour on Earth saying, "Ladies and gentlemen, from the dread capital of the world, Hollwood, California, Omega and the Mechanical Animals".

Is perhaps best known to younger audiences as the voice of "Ansem" (Xehanort) in Kingdom Hearts (2002) (VG).

He has played complete opposite sides of the typical "marooned love triangle." In Dead Calm (1989), he played the handsome and mysterious stranger who gets marooned with Sam Neill (the husband) and Nicole Kidman (wife). In Three (2005), he plays the jealous husband, in opposition to Kelly Brook (wife) and Juan Pablo Di Pace (handsome outsider).

Added more muscle to his already buff physique in order to effectively play Marc Antony in the 1999 movie Cleopatra (1999) (TV).

Is of Greek descent. Original family name is Tzanetakos.

Brother of actress Lisa Zane.

He attended The American School in Switzerland for his sophmore year of high school.

Billy attended Parker School in Chicago and Harand Camp of the Theater Arts in Elkhart Lake, Wisconsin with Jeremy Piven.

He has filmed movies in over 19 countries, including Australia 5 times.

He pumped iron for over a year to play his title role in The Phantom (1996).

Engaged to English actress Kelly Brook.

Is an avid swimmer and started shaving his head in 1997 for aerodynamics.

Was originally cast as Johnny Castle in Dirty Dancing (1987). During a dance rehearsal, Emile Ardolino realized that Zane could not dance, so they gave the part to Patrick Swayze.

Was engaged to Leonor Varela.